DNA Nanorobotics

نویسندگان

  • Harish Chandran
  • Nikhil Gopalkrishnan
  • John Reif
چکیده

This chapter overviews the current state of the emerging discipline of 4 DNA nanorobotics that make use of synthetic DNA to self-assemble operational 5 molecular-scale devices. Recently there have been a series of quite astonishing 6 experimental results—which have taken the technology from a state of intriguing 7 possibilities into demonstrated capabilities of quickly increasing scale and com8 plexity. We first state the challenges in molecular robotics and discuss why DNA as 9 a nanoconstruction material is ideally suited to overcome these. We then review the 10 design and demonstration of a wide range of molecular-scale devices; from DNA 11 nanomachines that change conformation in response to their environment to DNA 12 walkers that can be programmed to walk along predefined paths on nanostructures 13 while carrying cargo or performing computations, to tweezers that can repeatedly 14 switch states. We conclude by listing major challenges in the field along with some 15 possible future directions. 16 18.

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تاریخ انتشار 2011